Clinical review: Tokyo - protecting the health care worker during a chemical mass casualty event: an important issue of continuing relevance.

abstract：INTRODUCTION:The choice of invasive systemic haemodynamic monitoring in critically ill patients remains controversial as no multicentre comparative clinical data exist. Accordingly, we sought to study and compare the features and outcomes of patients who receive haemodynamic monitoring with either the pulmonary artery ...

journal_title：Critical care (London, England)

authors： Uchino S,Bellomo R,Morimatsu H,Sugihara M,French C,Stephens D,Wendon J,Honore P,Mulder J,Turner A,PAC\/PiCCO Use and Likelihood of Success Evaluation PULSE Study Group.

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Omega-3 (ω-3) fatty acid (FA)-containing parenteral nutrition (PN) is associated with significant improvements in patient outcomes compared with standard PN regimens without ω-3 FA lipid emulsions. Here, we evaluate the impact of ω-3 FA-containing PN versus standard PN on clinical outcomes and costs in adult...

journal_title：Critical care (London, England)

authors： Pradelli L,Klek S,Mayer K,Omar Alsaleh AJ,Rosenthal MD,Heller AR,Muscaritoli M

更新日期：2020-11-03 00:00:00

abstract：INTRODUCTION:Mobilisation of patients in the intensive care unit (ICU) is an area of growing research. Currently, there is little data on baseline mobilisation practises and the barriers to them for patients of all admission diagnoses. METHODS:The objectives of the study were to (1) quantify and benchmark baseline lev...

journal_title：Critical care (London, England)

authors： Harrold ME,Salisbury LG,Webb SA,Allison GT,Australia and Scotland ICU Physiotherapy Collaboration.

更新日期：2015-09-14 00:00:00

abstract：:Progress in management of critically ill neurological patients has led to improved survival rates. However, severe residual neurological impairment, such as persistent coma, occurs in some survivors. This raises concerns about whether it is ethically appropriate to apply aggressive care routinely, which is also associ...

journal_title：Critical care (London, England)

authors： Weiss N,Galanaud D,Carpentier A,Naccache L,Puybasset L

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Prophylactic steroid therapy to reduce the occurrence of postextubation laryngeal edema is controversial. Only a limited number of prospective trials involve adults in an intensive care unit. The purpose of this study was to ascertain whether administration of multiple doses of dexamethasone to critically ...

journal_title：Critical care (London, England)

authors： Lee CH,Peng MJ,Wu CL

更新日期：2007-01-01 00:00:00

abstract：:Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but m...

journal_title：Critical care (London, England)

authors： Bouglé A,Rocheteau P,Sharshar T,Chrétien F

更新日期：2016-05-19 00:00:00

abstract：:Bacterial pathogens possess an array of specific mechanisms that confer virulence and the capacity to avoid host defence mechanisms. Mechanisms of virulence are often mediated by the subversion of normal aspects of host biology. In this way the pathogen modifies host function so as to promote the pathogen's survival o...

journal_title：Critical care (London, England)

authors： Webb SA,Kahler CM

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:The aim of the study was to evaluate the ability of different static and dynamic measurements of preload to predict fluid responsiveness in patients with spontaneous respiratory movements. METHODS:The subjects were 21 critically ill patients with spontaneous breathing movements receiving mechanical ventil...

journal_title：Critical care (London, England)

authors： Heenen S,De Backer D,Vincent JL

更新日期：2006-01-01 00:00:00

abstract：:This review documents important progress made in 2013 in the field of critical care respirology, in particular with regard to acute respiratory failure and acute respiratory distress syndrome. Twenty-five original articles published in the respirology and critical care sections of Critical Care are discussed in the fo...

journal_title：Critical care (London, England)

authors： Curley GF,Slutsky AS

更新日期：2014-10-15 00:00:00

abstract：INTRODUCTION:Blood transfusion is associated with increased morbidity and mortality in cardiac surgery patients, but cause-and-effect relations remain unknown. We hypothesized that blood transfusion is associated with changes in pulmonary and systemic inflammation and coagulation occurring in patients who do not meet t...

journal_title：Critical care (London, England)

authors： Tuinman PR,Vlaar AP,Cornet AD,Hofstra JJ,Levi M,Meijers JC,Beishuizen A,Schultz MJ,Groeneveld AJ,Juffermans NP

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Dynamic predictors of fluid responsiveness, namely systolic pressure variation, pulse pressure variation, stroke volume variation and pleth variability index have been shown to be useful to identify in advance patients who will respond to a fluid load by a significant increase in stroke volume and cardiac ...

journal_title：Critical care (London, England)

authors： Benes J,Giglio M,Brienza N,Michard F

更新日期：2014-10-28 00:00:00

abstract：INTRODUCTION:Unawareness of an asymmetry between the right and left internal jugular vein (IJV) and methodological pitfalls in previous studies raise concerns about such asymmetry. Hence the aim of this prospective non-interventional study was to validate the hypothesis that right IJV diameter is greater than those of ...

journal_title：Critical care (London, England)

authors： Tartière D,Seguin P,Juhel C,Laviolle B,Mallédant Y

更新日期：2009-01-01 00:00:00

abstract：:Carbon dioxide is a waste product of aerobic cellular respiration in all aerobic life forms. PaCO2 represents the balance between the carbon dioxide produced and that eliminated. Hypocapnia remains a common - and generally underappreciated - component of many disease states, including early asthma, high-altitude pulmo...

journal_title：Critical care (London, England)

authors： Curley G,Laffey JG,Kavanagh BP

更新日期：2010-01-01 00:00:00

abstract：:The past 25 years have witnessed the development of improved tools with which to predict short-term and long-term outcomes after critical illness. The general paradigm for constructing the best known tools has been the logistic regression model. Recently, a variety of alternative tools, such as artificial neural netwo...

journal_title：Critical care (London, England)

authors： Clermont G

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Bacterial meningitis (BM) is a severe complication in patients with aneurysmal subarachnoid haemorrhage (SAH). Clinical signs of meningitis are often masked by SAH-related symptoms, and routine cerebrospinal fluid (CSF) analysis fails to indicate BM. Microdialysis (MD) is a technique for monitoring cerebra...

journal_title：Critical care (London, England)

authors： Schlenk F,Frieler K,Nagel A,Vajkoczy P,Sarrafzadeh AS

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether using pharmacodynamic-based dosing of antimicrobials, such as extended/continuous infusions, in critically ill patients is associated with improved outcomes as compared with traditional dosing methods. METHODS:We searched Medline, HealthStar, EMBASE, Cochrane...

journal_title：Critical care (London, England)

authors： Chant C,Leung A,Friedrich JO

更新日期：2013-11-29 00:00:00

abstract：BACKGROUND:Intensive care units (ICUs) face financial, bed management, and staffing constraints. Detailed data covering all aspects of patients' journeys into and through intensive care are now collected and stored in electronic health records: machine learning has been used to analyse such data in order to provide dec...

journal_title：Critical care (London, England)

authors： Shillan D,Sterne JAC,Champneys A,Gibbison B

更新日期：2019-08-22 00:00:00

abstract：PURPOSE:The histopathology of sepsis-associated acute kidney injury (AKI) in critically ill patients remains an understudied area. Previous studies have identified that acute tubular necrosis (ATN) is not the only driver of sepsis-AKI. The focus of this study was to identify additional candidate processes that may driv...

journal_title：Critical care (London, England)

authors： Aslan A,van den Heuvel MC,Stegeman CA,Popa ER,Leliveld AM,Molema G,Zijlstra JG,Moser J,van Meurs M

更新日期：2018-12-27 00:00:00

abstract：:Hypertension is an extremely common clinical problem, affecting approximately 50 million people in the USA and approximately 1 billion individuals worldwide. Approximately 1% of these patients will develop acute elevations in blood pressure at some point in their lifetime. A number of terms have been applied to severe...

journal_title：Critical care (London, England)

authors： Varon J,Marik PE

更新日期：2003-10-01 00:00:00

abstract：INTRODUCTION:The goal of personalised medicine in the intensive care unit (ICU) is to predict which diagnostic tests, monitoring interventions and treatments translate to improved outcomes given the variation between patients. Unfortunately, processes such as gene transcription and drug metabolism are dynamic in the cr...

journal_title：Critical care (London, England)

authors： Celi LA,Hinske LC,Alterovitz G,Szolovits P

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Kidney congestion is a common pathophysiologic pathway of acute kidney injury (AKI) in sepsis and heart failure. There is no noninvasive tool to measure kidney intracapsular pressure (KIP) directly. METHODS:We evaluated the correlation of KIP with kidney elasticity measured by ultrasound surface wave elasto...

journal_title：Critical care (London, England)

authors： Kashani KB,Mao SA,Safadi S,Amiot BP,Glorioso JM,Lieske JC,Nyberg SL,Zhang X

更新日期：2017-10-19 00:00:00

abstract：INTRODUCTION:Protocols using high levels of positive end-expiratory pressure (PEEP) in combination with low tidal volumes have been shown to reduce mortality in patients with severe acute respiratory distress syndrome (ARDS). However, the optimal method for setting PEEP is yet to be defined. It has been shown that resp...

journal_title：Critical care (London, England)

authors： Kostic P,Zannin E,Andersson Olerud M,Pompilio PP,Hedenstierna G,Pedotti A,Larsson A,Frykholm P,Dellaca RL

更新日期：2011-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the critically ill and is associated with adverse outcomes. Although there are plausible benefits from conversion and maintenance of sinus rhythm (the so-called 'rhythm-control' strategy), recent randomized trials have failed to demonstrate th...

journal_title：Critical care (London, England)

authors： Lim HS,Hamaad A,Lip GY

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:Recent evidence suggests a link between excess lipid peroxidation and specific organ failures in sepsis. No study has been performed in sepsis by multidrug-resistant (MDR) Gram-negative bacteria. METHODS:Lethal sepsis was induced in rats by the intraperitoneal injection of one MDR isolate of Pseudomonas a...

journal_title：Critical care (London, England)

authors： Toufekoula C,Papadakis V,Tsaganos T,Routsi C,Orfanos SE,Kotanidou A,Carrer DP,Raftogiannis M,Baziaka F,Giamarellos-Bourboulis EJ

更新日期：2013-01-16 00:00:00

abstract：INTRODUCTION:Despite recommendations from professional societies and patient safety organizations, the majority of ICU patients worldwide are not routinely monitored for delirium, thus preventing timely prevention and management. The purpose of this systematic review is to summarize what types of implementation strateg...

journal_title：Critical care (London, England)

authors： Trogrlić Z,van der Jagt M,Bakker J,Balas MC,Ely EW,van der Voort PH,Ista E

更新日期：2015-04-09 00:00:00

abstract：INTRODUCTION:The aim of the present multicenter study was to assess long term (36 months) health related quality of life in patients after critical illness, compare ICU survivors health related quality of life to that of the general population and examine the impact of pre-existing disease and factors related to ICU ca...

journal_title：Critical care (London, England)

authors： Orwelius L,Nordlund A,Nordlund P,Simonsson E,Bäckman C,Samuelsson A,Sjöberg F

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The overall prognosis of critically ill patients with cancer has improved during the past decade. The aim of this study was to identify early prognostic factors of intensive care unit (ICU) mortality in patients with cancer. METHODS:We designed a prospective, consecutive, observational study over a one-ye...

journal_title：Critical care (London, England)

authors： Mokart D,Sannini A,Brun JP,Faucher M,Blaise D,Blache JL,Faucher C

更新日期：2007-01-01 00:00:00

abstract：:In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflammatory effects afte...

journal_title：Critical care (London, England)

authors： Zhang H

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The objective was to study the effects of a novel lung volume optimization procedure (LVOP) using high-frequency oscillatory ventilation (HFOV) upon gas exchange, the transpulmonary pressure (TPP), and hemodynamics in a porcine model of surfactant depletion. METHODS:With institutional review board approva...

journal_title：Critical care (London, England)

authors： Karmrodt J,David M,Yuan S,Markstaller K

更新日期：2006-01-01 00:00:00

abstract：:There are many controversial issues surrounding ethics in study design and conduct of human subjects research. In this review we briefly touch on the origin of ethics in clinical research and how the current regulations and standards came into practice. We then discuss current controversies regarding informed consent,...

journal_title：Critical care (London, England)

authors： Huang DT,Hadian M

更新日期：2006-01-01 00:00:00