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Pituitary and bilateral adrenal enlargement: an unusual presentation of hepatocellular carcinoma.

Abstract：

:Pituitary metastases account for about 1% of operated pituitary lesions. Most derive from primaries in the breast or lung. Pituitary metastases from hepatocellular carcinoma (HCC) have rarely been reported. We describe a patient in whom headache and left external ophthalmoplegia were the only presenting signs of a clinically silent and radiographically undetectable HCC, that had metastasized to the pituitary and both adrenal glands. Pituitary histology and adrenal needle biopsy failed to establish the final diagnosis, which was reached only after surgical exploration of the abdomen. This case illustrates the difficulties encountered in the histopathological diagnosis of pituitary metastasis and the need for good clinical judgment when confronting pituitary tumors with atypical features.

journal_name

J Endocrinol Invest

journal_title

Journal of endocrinological investigation

authors

Hirsch D,Benbassat CA,Drozd T,Okon E,Blum I

doi

10.1007/BF03347227

keywords:

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

454-8

issue

5

eissn

0391-4097

issn

1720-8386

pii

3151

journal_volume

28

pub_type

杂志文章

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