Preliminary data suggest that mutations in the CgRP pathway are not involved in human sporadic cryptorchidism.

abstract：:The occurrence of tumors originating from aberrant adrenocortical tissue in ectopic site is very rare. Up to now only two cases of ectopic aldosterone-producing adenoma have been described. We have observed another case of ectopic aldosteronoma, located in the retrocaval region, laterally to the body of the 12th thora...

journal_title：Journal of endocrinological investigation

authors： Mazza E,Papotti M,Durando R,Robecchi A,Camanni F

更新日期：1995-11-01 00:00:00

abstract：:This report describes the results of the second part of the collaborative study organized by a working group sponsored by the Community Bureau of Reference of the European Community Commission. The whole study was designed to understand the causes of discrepancy among LH immunoassay methods. In the parent report we de...

journal_title：Journal of endocrinological investigation

authors： Costagliola S,Niccoli P,Florentino M,Carayon P

更新日期：1994-06-01 00:00:00

abstract：:Resveratrol, the naturally occurring polyphenolic compound characterized by anti-oxidative, anti-inflammatory and apoptotic properties, appears to contribute substantially to cardioprotection and cancer-prevention. In addition, resveratrol is believed to regulate several biological processes, mainly metabolism and agi...

journal_title：Journal of endocrinological investigation

authors： Duntas LH

更新日期：2011-11-01 00:00:00

abstract：UNLABELLED:Hexarelin (HEX) is a synthetic hexapeptide with strong GH-stimulating activity. We evaluated GH response (expressed as maximum value after stimulus [Cmax] and as area under the curve [AUC]) to HEX at the doses of 1 microg/kg i.v. (HEX 1) and 2 microg/kg i.v. (HEX 2), in comparison with the responses to GHRH ...

journal_title：Journal of endocrinological investigation

authors： Guzzaloni G,Grugni G,Morabito F

更新日期：1999-05-01 00:00:00

abstract：:The DAZ (deleted in azoospermia) gene family is considered the major AZFc ("azoospermia factor" c) candidate responsible for male infertility. However, other genes have been recently mapped to this region and they could contribute to the AZFc phenotype. In particular, the testis-specific CDY1 (chromadomain protein 1) ...

journal_title：Journal of endocrinological investigation

authors： Ferlin A,Moro E,Rossi A,Foresta C

更新日期：2001-02-01 00:00:00

abstract：:The multiple effects of vitamin D on skeletal and extra-skeletal tissues increased the attention of scientists and public to the possible relationship between hypovitaminosis D and a variety of acute and chronic diseases. However, several points are still largely debated. In particular, the definition of optimal vitam...

journal_title：Journal of endocrinological investigation

authors： Romagnoli E,Carnevale V,Biondi P,Minisola S

更新日期：2014-07-01 00:00:00

abstract：:We report an original application of quantitative reverse transcription-polymerase chain reaction (Q.RT-PCR) for the evaluation of atrial natriuretic factor (ANF), brain natriuretic peptide (BNP) and beta-actin mRNA in small atrial samples (10-15 mg). A fixed amount of total RNA was simultaneously reverse transcribed ...

journal_title：Journal of endocrinological investigation

authors： Iascone MR,Vittorini S,Collavoli A,Cupelli A,Kraft G,Biagini A,Clerico A

更新日期：1999-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the possible association of insulin-like growth factor-1 (IGF-1) with the pathogenesis of non-functioning adrenocortical adenomas (NFAs). METHODS:This study included 50 female patients (mean age 54 years) with NFAs, 55 patients (mean age 48 years; 20 male, 35 female) wi...

journal_title：Journal of endocrinological investigation

authors： Bahadir CT,Ecemis GC,Atmaca H

更新日期：2018-11-01 00:00:00

abstract：:IGF-I stimulates protein synthesis, lowers blood glucose, and affects cell differentiation. The main production site of IGF-I is the liver. One of its binding proteins, IGFBP-1, is also produced by the liver. It is well known that ethanol affects the function of the human liver. Long-term alcohol abuse may therefore n...

journal_title：Journal of endocrinological investigation

authors： Röjdmark S,Brismar K

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Increased inhibin A serum and plasma levels in the second trimester are significantly associated with the development of preeclampsia. The measurement of inhibin A during early pregnancies may be helpful to predict those at risk of this disorder. The purpose of this study was to determine whether the 769G>A v...

journal_title：Journal of endocrinological investigation

authors： Kim SY,Lim JH,Yang JH,Kim MY,Kim MH,Park SY,Ryu HM

更新日期：2008-08-01 00:00:00

abstract：:This study, carried out on 9 nonfunctioning pituitary adenomas, was undertaken in order to evaluate the ability of these tumors to synthesize and release gonadotropins and/or free alpha-subunit (alpha-SU) of glycoproteins. The morphological study included electron microscopy and immunofluorescence analysis while hormo...

journal_title：Journal of endocrinological investigation

authors： Saccomanno K,Gil del Alamo P,Bassetti M,Reza-Elahi F,Spada A

更新日期：1993-02-01 00:00:00

abstract：:In 1939 Alan Turing, a major scholar in the field of mechanical computation, described a system whose computational power was beyond that of a discrete, finite state machine (Turing Machine). The composition of this system was likely the first example of what is now called an hybrid computational system. Since then, d...

journal_title：Journal of endocrinological investigation

authors： Sandri G

更新日期：2004-01-01 00:00:00

abstract：:Thyrocytes from normal and goitrous portions of the thyroid gland from a patient with an enormous (635 gm) goiter were cultured in media, and their relative abilities to uptake thymidine, synthesize DNA, and secrete Tg and T4 were assessed. Tg, T4 and the ratio Tg/T4 in media at 72 h were 120 micrograms/dl, 1.6 microg...

journal_title：Journal of endocrinological investigation

authors： Tseng YC,Burman KD,Baker JR Jr,D'Avis J,Wartofsky L

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:Elimination of thyroid antigens by total thyroid ablation (TTA), namely, thyroidectomy followed by radioiodine, may be beneficial for Graves' Orbitopathy (GO). TTA is usually performed with a 131I dose of 30 mCi. In Italy, this dose must be followed by a 24-h protected hospitalization, with increase in the wa...

journal_title：Journal of endocrinological investigation

authors： Leo M,Sabini E,Ionni I,Sframeli A,Mazzi B,Menconi F,Molinaro E,Bianchi F,Brozzi F,Santini P,Elisei R,Nardi M,Vitti P,Marcocci C,Marinò M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Successful parathyroidectomy (PTX) often results in a dramatic drop in the parathyroid hormone (PTH) levels, relieves the patient from clinical symptoms, and reduces mortality. Although PTX is generally a successful treatment for progressive secondary hyperparathyroidism (SHPT) patients subjected to surgery,...

journal_title：Journal of endocrinological investigation

authors： Xu D,Yin Y,Hou L,Dai W

更新日期：2016-05-01 00:00:00

abstract：:Pituitary adenomas are common neoplasms requiring medical and/or surgical treatment when associated with hormonal hypersecretion. Treatment of non-functioning pituitary adenomas is necessary when symptoms of mass effect or hormonal deficits occur. However, therapeutic options, including surgical resection and/or radio...

journal_title：Journal of endocrinological investigation

authors： Ballian N,Chrisoulidou A,Nomikos P,Samara C,Kontogeorgos G,Kaltsas GA

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Due to the lack of specific pediatric studies, no data are available about natural history of endogenous subclinical hyperthyroidism (SH) in childhood. AIMS:(a) To investigate for the first time the natural history of SH [suppressed thyrotropin (TSH) and normal free thyroxine free thyroxine (FT4) levels] wh...

journal_title：Journal of endocrinological investigation

authors： Aversa T,Valenzise M,Corrias A,Salerno M,Mussa A,Capalbo D,Salzano G,De Luca F,Wasniewska M

更新日期：2014-03-01 00:00:00

abstract：:Two radioimmunological techniques for the measurement of anti-alpha-galactosyl (anti-Gal) antibodies were developed and we demonstrated that this antibody is present in the serum of most untreated patients with Graves' disease, thyroid-associated ophthalmopathy (TAO) and autoimmune thyroiditis. Thyrotropin-binding inh...

journal_title：Journal of endocrinological investigation

authors： Winand RJ,Winand-Devigne J,Cox C,Caulier C,Meurisse M

更新日期：1995-11-01 00:00:00

abstract：:It has recently been suggested that the classical routine of glucocorticoid administration before and after transsphenoidal surgery (TSS) in Cushing's disease (CD) patients may not be necessary, since it is likely that peritumoral normal corticotrophs are not completely suppressed during this period. We compared the d...

journal_title：Journal of endocrinological investigation

authors： Pimentel-Filho FR,Silva ME,Nogueira KC,Berger K,Cukiert A,Liberman B

更新日期：2005-06-01 00:00:00

abstract：:The renin-angiotensin-aldosterone system (RAAS) plays a well-recognized role in the regulation of BP and in salt and water balance. Since hypertension affects a considerable proportion of obese patients, circulating RAAS has been studied in obese subjects with and without hypertension, albeit with conflicting results....

journal_title：Journal of endocrinological investigation

authors： Faloia E,Gatti C,Camilloni MA,Mariniello B,Sardu C,Garrapa GG,Mantero F,Giacchetti G

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:In our previous study, we introduced a rat model of polycystic ovary syndrome (PCOS) induced by prenatal exposure to a single dose of testosterone on embryonic day 20. In the current study, we aimed to investigate whether prenatal exposure to a single dose of testosterone could also induce metabolic disturbance...

journal_title：Journal of endocrinological investigation

authors： Noroozzadeh M,Ramezani Tehrani F,Sedaghat K,Godini A,Azizi F

更新日期：2015-05-01 00:00:00

abstract：:The last decade has witnessed an upsurge of interest in the research on facial attractiveness. The development of computer graphics has allowed to objectively investigate the conserved features of attractive faces. Averageness, symmetry and sex-specific traits have been associated with attractiveness. The effect of av...

journal_title：Journal of endocrinological investigation

authors： Cellerino A

更新日期：2003-01-01 00:00:00

abstract：:The effect of the somatostatin analog (GHRIH-A) D-Trp8, D-Cys14 on plasma levels of growth hormone, pancreatic glucagon, insulin and glucose was studied in four acromegalic patients and in four maturity-onset mild diabetics. Acromegalics received a bolus iv injection of 25 microgram of GHRIH-A, followed by a continuou...

journal_title：Journal of endocrinological investigation

authors： Trovati M,Massara F,Camanni F,Molinatti GM,Lorenzati R,Pagano GF

更新日期：1980-04-01 00:00:00

abstract：UNLABELLED:Hypercalcemia occurring in patients with advanced breast cancer (BC) is generally due to osteolytic metastases or to the activity of circulating tumor-derived products. In these conditions, the production of endogenous PTH is reduced. The frequency of hypercalcemia due to primary hyperparathyroidism in breas...

journal_title：Journal of endocrinological investigation

authors： Fierabracci P,Pinchera A,Miccoli P,Conte PF,Vignali E,Zaccagnini M,Marcocci C,Giani C

更新日期：2001-05-01 00:00:00

abstract：:Pituitary collision tumors are rare. They may create difficult diagnostic problems and their histogenesis is not clear. We report here an unusual case of a somatotroph adenoma colliding with a gonadotroph adenoma.The 64-year-old man had clinical acromegaly. His blood growth hormone level was elevated and magnetic reso...

journal_title：Journal of endocrinological investigation

authors： Syro LV,Horvath E,Kovacs K

更新日期：2000-01-01 00:00:00

abstract：:Pituitary metastases account for about 1% of operated pituitary lesions. Most derive from primaries in the breast or lung. Pituitary metastases from hepatocellular carcinoma (HCC) have rarely been reported. We describe a patient in whom headache and left external ophthalmoplegia were the only presenting signs of a cli...

journal_title：Journal of endocrinological investigation

authors： Hirsch D,Benbassat CA,Drozd T,Okon E,Blum I

更新日期：2005-05-01 00:00:00

abstract：:Differently from other metabolic conditions, most of calcium metabolism disorders are diagnosed through simple detection of both serum and urinary excretion (24-h urine collection), levels of calcium, total and ionized form, and phosphate, and of calciotropic hormone serum levels, such as calcitonin, PTH and vitamin D...

journal_title：Journal of endocrinological investigation

authors： Cioppi F,Falchetti A,Masi L,Brandi ML

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:Female Sexual Dysfunction (FSD) is a still poorly studied and underdiagnosed condition. The aim of the study was to produce an improved version of FSFI-6 (6-Item Version of the Female Sexual Function Index), entitled Female Sexual Dysfunction Index-6 (FSDI-6), and to estimate its accuracy as a screening instrum...

journal_title：Journal of endocrinological investigation

authors： Maseroli E,Fanni E,Fambrini M,Ragghianti B,Limoncin E,Mannucci E,Maggi M,Vignozzi L

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors determine a wide reduction of LDL cholesterol, greater than other lipid-lowering agents. The present meta-analysis is aimed at the assessment of PCSK9 inhibitors effect on LDL Cholesterol, cardiovascular morbidity and all-cause mortali...

journal_title：Journal of endocrinological investigation

authors： Dicembrini I,Giannini S,Ragghianti B,Mannucci E,Monami M

更新日期：2019-09-01 00:00:00

abstract：:D-aspartic acid (D-Asp), aromatase enzyme activity and the putative D-Asp involvement on aromatase induction have been studied in the testis of mature boars. The peroxidase-antiperoxidase and the indirect immunofluorescence methods, applied to cryostat and paraffin sections, were used to evaluate D-Asp and aromatase d...

journal_title：Journal of endocrinological investigation

authors： Lamanna C,Assisi L,Botte V,Di Fiore MM

更新日期：2006-02-01 00:00:00