Endothelin and post-ganglionic sympathetic neurons.

Abstract:

:1. The present report documents evidence suggesting that endothelin (ET) is a mediator and modulator of post-ganglionic sympathetic neuronal development. 2. Endothelin is produced by post-ganglionic neurons and by cells adjacent to these neurons. 3. Post-ganglionic sympathetic neurons express functional receptors for ET. 4. Endothelin promotes the survival of cultured post-ganglionic sympathetic neurons and modulates the morphological and biochemical differentiation of these neurons. 5. Endothelin enhances the activity of nerve growth factor and modulates the release of neurotransmitter from post-ganglionic sympathetic nerve terminals.

authors

Damon DH

doi

10.1046/j.1440-1681.1999.03179.x

keywords:

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

1000-3

issue

12

eissn

0305-1870

issn

1440-1681

journal_volume

26

pub_type

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