当前位置： SCI文献检索 > JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH期刊下所有文献 > Serum soluble Fas antigen in gastric MALT (mucosa-associated lymphoid tissue) lymphoma patients.

Serum soluble Fas antigen in gastric MALT (mucosa-associated lymphoid tissue) lymphoma patients.

Abstract：

:We measured the serum level of soluble Fas (sFas) antigen in gastric MALT (mucosa-associated lymphoid tissue) lymphoma patients to investigate immune response of B lymphoma cells in gastric MALT lymphoma. The serum sFas antigen levels in 21 patients with Helicobacter pylori (HP)-positive MALT lymphoma were 4.51+/-0.25 (mean+/-SD) in the high grade malignant group (n=9) that demonstrated diffuse large cell (DL) components and 2.53+/-0.46 (mean+/-SD) in the low grade malignant group (n=12) that did not demonstrate DL components. Among 12 patients who underwent HP eradication therapy, the blood sFas antigen level lowered after eradication in 7 out of 10 patients who showed complete response or partial response, while sFas antigen level did not decrease in the 2 patients who showed no change or progression of the disease. In the high grade malignant group, 2 of 3 patients who underwent HP eradication treatment showed a mild decrease in the sFas antigen level as well as an improvement on endoscopic and histological examinations, but these sFas level were not normalized. The blood sFas antigen level tended to coincide with pathological activity and malignancy, suggesting that the sFas antigen level may be a prognostic indicator and useful index for the response of HP eradication treatment in gastric MALT lymphoma.

journal_name

J Exp Clin Cancer Res

journal_title

Journal of experimental & clinical cancer research : CR

authors

Doi T,Nishikawa Y,Endo H,Hosokawa Y,Tanimizu M,Hyodo I

keywords:

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

343-5

issue

3

eissn

0392-9078

issn

1756-9966

journal_volume

18

pub_type

杂志文章

相关文献

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH文献大全
  • A classification of problems regarding gut endocrinomas (carcinoids and relevant neoplasms).

    abstract：:In the field of gut endocrinomas (carcinoids and relevant neoplasms), several classifications have been internationally accepted and utilized at varying frequency. The basis of the concepts regarding gut endocrinomas from which these classifications have been proposed were drawn from the different aspects. These inclu...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,评审

    doi：

    authors： Soga J,Yakuwa Y,Osaka M

    更新日期：1999-03-01 00:00:00

  • Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway.

    abstract：BACKGROUND:Melanomas are highly malignant and have high metastatic potential; hence, there is a need for new therapeutic strategies to prevent cell metastasis. In the present study, we investigated whether statins inhibit tumor cell migration, invasion, adhesion, and metastasis in the B16BL6 mouse melanoma cell line. ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/1756-9966-29-127

    authors： Kidera Y,Tsubaki M,Yamazoe Y,Shoji K,Nakamura H,Ogaki M,Satou T,Itoh T,Isozaki M,Kaneko J,Tanimori Y,Yanae M,Nishida S

    更新日期：2010-09-16 00:00:00

  • MiR-200c sensitizes Olaparib-resistant ovarian cancer cells by targeting Neuropilin 1.

    abstract：BACKGROUND:Ovarian cancer (OC) is the most lethal gynecological malignancy and the second leading cause of cancer-related death in women. Treatment with PARP inhibitors (PARPi), such as Olaparib, has been recently introduced for OC patients, but resistance may occur and underlying mechanisms are still poorly understood...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-019-1490-7

    authors： Vescarelli E,Gerini G,Megiorni F,Anastasiadou E,Pontecorvi P,Solito L,De Vitis C,Camero S,Marchetti C,Mancini R,Benedetti Panici P,Dominici C,Romano F,Angeloni A,Marchese C,Ceccarelli S

    更新日期：2020-01-02 00:00:00

  • Obstructive biliary symptomatology as the first sign of HIV-infection.

    abstract：:A 41-year-old white homosexual man presented with epigastric pain and jaundice. Physical examination showed enlargement of bilateral axillar and left inguinal lymph node, while ERCP and a CT scan suggested interruption of bile flow in the intrapancreatic tract of the common bile duct. An endoprosthesis was positioned ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：

    authors： De Toma G,Codacci-Pisanelli M,Nicolanti V,Plocco M,Caterino S,Perno CF

    更新日期：1999-12-01 00:00:00

  • CDK4 IVS4-nt40 AA genotype and obesity-associated tumors/cancer in Italians - a case-control study.

    abstract：BACKGROUND:Cell cycle checkpoint regulation is crucial for prevention of tumor in mammalian cells. Cyclin-dependant kinase 4 (CDK4) is important in cell cycle regulation, as it controls the G1-S phase of the cell cycle. CDK4 has potential mitogenic properties through phosphorylation of target proteins. We aimed at iden...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/1756-9966-28-42

    authors： Meenakshisundaram R,Gragnoli C

    更新日期：2009-03-28 00:00:00

  • miR-539 inhibits prostate cancer progression by directly targeting SPAG5.

    abstract：BACKGROUND:We conducted multiple microarray datasets analyses from clinical and xenograft tumor tissues to search for disease progression-driving oncogenes in prostate cancer (PCa). Sperm-associated antigen 5 (SPAG5) attracted our attention. SPAG5 was recently identified as an oncogene participating in lung cancer and ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-016-0337-8

    authors： Zhang H,Li S,Yang X,Qiao B,Zhang Z,Xu Y

    更新日期：2016-04-01 00:00:00

  • Significance of overexpression of alpha methylacyl-coenzyme A racemase in hepatocellular carcinoma.

    abstract：BACKGROUND:alpha-Methylacyl-CoA racemase (AMACR), an immunomarker for prostatic adenocarcinoma, has been shown to be expressed in a variety of other neoplasms. This study aims to evaluate immunohistochemical expression of the AMACR in neoplastic and nonneoplastic liver lesions, and assess its value in the diagnosis of ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/1756-9966-27-2

    authors： Li W,Cagle PT,Botero RC,Liang JJ,Zhang Z,Tan D

    更新日期：2008-05-15 00:00:00

  • Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells.

    abstract：BACKGROUND:CD147 plays a critical role in the invasive and metastatic activity of hepatocellular carcinoma (HCC) cells by stimulating the surrounding fibroblasts to express matrix metalloproteinases (MMPs). Tumor cells adhesion to extracellular matrix (ECM) proteins is the first step to the tumor metastasis. MMPs degra...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/1756-9966-27-50

    authors： Qian AR,Zhang W,Cao JP,Yang PF,Gao X,Wang Z,Xu HY,Weng YY,Shang P

    更新日期：2008-10-11 00:00:00

  • Mechanisms of hyperprogressive disease after immune checkpoint inhibitor therapy: what we (don't) know.

    abstract：:Immune checkpoint inhibitors (ICIs) have made a breakthrough in the treatment of different types of tumors, leading to improvement in survival, even in patients with advanced cancers. Despite the good clinical results, a certain percentage of patients do not respond to this kind of immunotherapy. In addition, in a fra...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,评审

    doi：10.1186/s13046-020-01721-9

    authors： Camelliti S,Le Noci V,Bianchi F,Moscheni C,Arnaboldi F,Gagliano N,Balsari A,Garassino MC,Tagliabue E,Sfondrini L,Sommariva M

    更新日期：2020-11-09 00:00:00

  • Efficacy and safety of ipilimumab in elderly patients with pretreated advanced melanoma treated at Italian centres through the expanded access programme.

    abstract：BACKGROUND:Elderly patients with metastatic melanoma have different disease characteristics and a poorer prognosis than younger patients. Data from clinical trials and expanded access programmes (EAPs) suggest ipilimumab confers a consistent survival benefit and has a similar safety profile across different age groups ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1186/1756-9966-33-30

    authors： Chiarion Sileni V,Pigozzo J,Ascierto PA,Grimaldi AM,Maio M,Di Guardo L,Marchetti P,de Rosa F,Nuzzo C,Testori A,Cocorocchio E,Bernengo MG,Guida M,Marconcini R,Merelli B,Parmiani G,Rinaldi G,Aglietta M,Grosso M,Queiro

    更新日期：2014-04-04 00:00:00

  • Gemcitabine sensitivity-related mRNA expression in endoscopic ultrasound-guided fine-needle aspiration biopsy of unresectable pancreatic cancer.

    abstract：BACKGROUND:The aim of this study was to determine a predictive indicator of gemcitabine (GEM) efficacy in unresectable pancreatic cancer using tissue obtained by endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA). METHODS:mRNAs extracted from 35 pancreatic tubular adenocarcinoma tissues obtained by E...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/1756-9966-28-83

    authors： Ashida R,Nakata B,Shigekawa M,Mizuno N,Sawaki A,Hirakawa K,Arakawa T,Yamao K

    更新日期：2009-06-16 00:00:00

  • Patient-derived xenografts: a relevant preclinical model for drug development.

    abstract：:Identifying appropriate preclinical cancer models remains a major challenge in increasing the efficiency of drug development. A potential strategy to improve patient outcomes could be selecting the 'right' treatment in preclinical studies performed in patient-derived xenografts (PDXs) obtained by direct implants of su...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,评审

    doi：10.1186/s13046-016-0462-4

    authors： Pompili L,Porru M,Caruso C,Biroccio A,Leonetti C

    更新日期：2016-12-05 00:00:00

  • 6-Gingerol stabilized the p-VEGFR2/VE-cadherin/β-catenin/actin complex promotes microvessel normalization and suppresses tumor progression.

    abstract：BACKGROUND:Anti-angiogenic therapies demonstrate anti-tumor effects by decreasing blood supply to tumors and inhibiting tumor growth. However, anti-angiogenic therapy may leads to changes in tumor microenvironment and increased invasiveness of tumor cells, which in turn promotes distant metastasis and increased drug re...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-019-1291-z

    authors： Zhong W,Yang W,Qin Y,Gu W,Xue Y,Tang Y,Xu H,Wang H,Zhang C,Wang C,Sun B,Liu Y,Liu H,Zhou H,Chen S,Sun T,Yang C

    更新日期：2019-07-02 00:00:00

  • Endoscopic palliative therapy in neoplastic diseases of the esophagus.

    abstract：:Over the past 20 years, fiberoptic endoscopy, followed by video-endoscopy, has taken on an increasingly important role in the diagnostics and therapy for digestive tract diseases. Especially in the field of oncology, endoscopy is fundamental not only for the diagnosis and staging of diseases of the gastroenteric tract...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,评审

    doi：

    authors： Casale V,Lapenta R,Gigliozzi A,Villotti G

    更新日期：1999-03-01 00:00:00

  • Complement C3 overexpression activates JAK2/STAT3 pathway and correlates with gastric cancer progression.

    abstract：BACKGROUND:Localized C3 deposition is a well-known factor of inflammation. However, its role in oncoprogression of gastric cancer (GC) remains obscured. This study aims to explore the prognostic value of C3 deposition and to elucidate the mechanism of C3-related oncoprogression for GC. METHODS:From August to December ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 临床试验,杂志文章

    doi：10.1186/s13046-019-1514-3

    authors： Yuan K,Ye J,Liu Z,Ren Y,He W,Xu J,He Y,Yuan Y

    更新日期：2020-01-13 00:00:00

  • GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment.

    abstract：BACKGROUND:The aim of this study was to investigate the effect of downregulating Hedgehog pathway by GANT61 on human glioma cells, examine the consequent changes of temozolomide (TMZ)-induced effects and explore the molecular mechanisms. METHODS:The cytotoxicity of a Gli1/2 inhibitor, GANT61 was examined both alone an...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-016-0463-3

    authors： Li J,Cai J,Zhao S,Yao K,Sun Y,Li Y,Chen L,Li R,Zhai X,Zhang J,Jiang C

    更新日期：2016-11-28 00:00:00

  • CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells.

    abstract：BACKGROUND:Coiled-Coil Domain Containing 88A (CCDC88A) was identified as a substrate of the serine/threonine kinase Akt that is capable of binding to the actin cytoskeleton. The aim of this study was to investigate the potential role of CCDC88A in the migration and invasiveness of pancreatic ductal adenocarcinoma (PDAC...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-016-0466-0

    authors： Tanouchi A,Taniuchi K,Furihata M,Naganuma S,Dabanaka K,Kimura M,Watanabe R,Kohsaki T,Shimizu T,Saito M,Hanazaki K,Saibara T

    更新日期：2016-12-05 00:00:00

  • SWATH-MS based quantitative proteomics analysis reveals that curcumin alters the metabolic enzyme profile of CML cells by affecting the activity of miR-22/IPO7/HIF-1α axis.

    abstract：BACKGROUND:Chronic myelogenous leukemia (CML) is a myeloproliferative disorder caused by expression of the chimeric BCR-ABL tyrosine kinase oncogene, resulting from the t(9;22) chromosomal translocation. Imatinib (gleevec, STI-571) is a selective inhibitor of BCR-ABL activity highly effective in the treatment of CML. H...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-018-0843-y

    authors： Monteleone F,Taverna S,Alessandro R,Fontana S

    更新日期：2018-07-25 00:00:00

  • Targeted radiotherapy of pigmented melanoma with 131I-5-IPN.

    abstract：PURPOSE:There has been no satisfactory treatment for advanced melanoma until now. Targeted radionuclide therapy (TRNT) may be a promising option for this heretofore lethal disease. Our goal in this study was to synthesize 131I-N-(2-(diethylamino)ethyl)-5-(iodo-131I)picolinamide (131I-5-IPN) and evaluate its therapeutic...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-018-0983-0

    authors： Xu X,Yuan L,Gai Y,Liu Q,Yin L,Jiang Y,Wang Y,Zhang Y,Lan X

    更新日期：2018-12-11 00:00:00

  • Non-coding RNAs in cancer: platforms and strategies for investigating the genomic "dark matter".

    abstract：:The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are candidates for therapeutic intervention, since they may act as biomarkers or key regulators of cancer gene network. Recently, profiling and sequenci...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,评审

    doi：10.1186/s13046-020-01622-x

    authors： Grillone K,Riillo C,Scionti F,Rocca R,Tradigo G,Guzzi PH,Alcaro S,Di Martino MT,Tagliaferri P,Tassone P

    更新日期：2020-06-20 00:00:00

  • Breast cancer and distress resulting from Magnetic Resonance Imaging (MRI): the impact of a psychological intervention of emotional and informative support.

    abstract：:The present study assesses the adaptation of a group of female patients with either manifest or suspected breast cancer who have undergone Magnetic Resonance Imaging (MRI) after receiving psychological support. Several studies in literature have reported the effectiveness of such support in reducing anti-oxidant and d...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：

    authors： Caruso A,Bongiorno L,Vallini L,Russo P,Tomao F,Grandinetti ML

    更新日期：2006-12-01 00:00:00

  • miR-589-5p inhibits MAP3K8 and suppresses CD90+ cancer stem cells in hepatocellular carcinoma.

    abstract：BACKGROUND:Cancer stem cells (CSCs) are important in the tumorigenesis and progression of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play crucial roles regulating CD133+ and EpCAM+ CSCs in HCC, although it is unclear whether miRNAs regulate CD90+ CSCs in HCC. METHODS:The miRNA profiles of CD90+ and CD90- HCC c...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-016-0452-6

    authors： Zhang X,Jiang P,Shuai L,Chen K,Li Z,Zhang Y,Jiang Y,Li X

    更新日期：2016-11-11 00:00:00

  • Cell death induction by the BH3 mimetic GX15-070 in thyroid carcinoma cells.

    abstract：BACKGROUND:The evasion of cell death is one of the hallmarks of cancer, contributing to both tumor progression and resistance to therapy. Dedifferentiated and anaplastic thyroid carcinomas that do not take up radioiodine are resistant to conventional anticancer treatments and patients with these tumors are difficult to...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-015-0186-x

    authors： Broecker-Preuss M,Viehof J,Jastrow H,Becher-Boveleth N,Fuhrer D,Mann K

    更新日期：2015-07-22 00:00:00

  • miR-4317 suppresses non-small cell lung cancer (NSCLC) by targeting fibroblast growth factor 9 (FGF9) and cyclin D2 (CCND2).

    abstract：BACKGROUND:Non-small cell lung cancer (NSCLC) is a leading cause of death worldwide. MicroRNAs (miRNAs) have been indicated as crucial actors in cancer biology. Accumulating evidence suggests that miRNAs can be used as diagnostic and prognostic markers for NSCLC. METHODS:The purpose of this study was to characterize a...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-018-0882-4

    authors： He X,Chen SY,Yang Z,Zhang J,Wang W,Liu MY,Niu Y,Wei XM,Li HM,Hu WN,Sun GG

    更新日期：2018-09-18 00:00:00

  • UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.

    abstract：BACKGROUND:Ubiquitin-like protein 4A (UBL4A) plays a significant role in protein metabolism and the maintenance of cellular homeostasis. In cancer, UBL4A represses tumorigenesis and is involved in various signaling pathways. Pancreatic ductal adenocarcinoma (PDAC) is still a major cause of cancer-related death and the ...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-019-1278-9

    authors： Chen H,Li L,Hu J,Zhao Z,Ji L,Cheng C,Zhang G,Zhang T,Li Y,Chen H,Pan S,Sun B

    更新日期：2019-07-09 00:00:00

  • CDK4/6 inhibitors: a novel strategy for tumor radiosensitization.

    abstract：:Recently, the focus of enhancing tumor radiosensitivity has shifted from chemotherapeutics to targeted therapies. Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are a novel class of selective cell cycle therapeutics that target the cyclin D-CDK4/6 complex and induce G1 phase arrest. These agents have demonstrated...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,评审

    doi：10.1186/s13046-020-01693-w

    authors： Yang Y,Luo J,Chen X,Yang Z,Mei X,Ma J,Zhang Z,Guo X,Yu X

    更新日期：2020-09-15 00:00:00

  • Sustained delivery of siRNA/PEI complex from in situ forming hydrogels potently inhibits the proliferation of gastric cancer.

    abstract：BACKGROUND:Gastric cancer remains a major cause of mortality and morbidity worldwide. In recent years, gene-based therapeutic strategies were confirmed promising in cancer inhibition and attracted great attention. RNA interference (RNAi) is a powerful tool for gene therapy and has been widely employed to aid in treatme...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：10.1186/s13046-016-0334-y

    authors： Peng H,Yang H,Song L,Zhou Z,Sun J,Du Y,Lu K,Li T,Yin A,Xu J,Wei S

    更新日期：2016-03-31 00:00:00

  • Breast cancer susceptibility gene 1 (BRCA1) predict clinical outcome in platinum- and toxal-based chemotherapy in non-small-cell lung cancer (NSCLC) patients: a system review and meta-analysis.

    abstract：:The recent studies have evaluated the relationship between BRCA1 expression and clinical outcome of chemotherapy (mainly focused on platinum-based and toxal-based treatment) in NSCLC patients, but the results were inconclusive and controversial. Our aim of this study was to evaluate this association by literature base...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,meta分析,评审

    doi：10.1186/1756-9966-32-15

    authors： Yang Y,Xie Y,Xian L

    更新日期：2013-03-15 00:00:00

  • Retraction Note: Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression.

    abstract：:The Editor-in-Chief has retracted this article [1] due to concerns about the figures. In Figure 3C, the images from the colony formation assays of all cell lines, excluding the control for the HCCLM9 cell line, contain identical patterns of colonies; this suggests that despite the fact they are supposed to be observat...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章,撤回出版物

    doi：10.1186/s13046-019-1224-x

    authors： Wang Y,Qin X,Guo T,Liu P,Wu P,Liu Z

    更新日期：2019-05-23 00:00:00

  • Primary non-Hodgkin lymphoma of the breast. Is it possible to avoid mastectomy?

    abstract：:Primary lymphoma of the breast is a rare disease that has been estimated to represent from 0.05% to 0.53% of all malignant breast tumors and approximately 2.2% of all extranodal lymphomas. The aim of this study is to review all cases of primary lymphoma of the breast at the Institute of Oncology and Radiology of Serbi...

    journal_title：Journal of experimental & clinical cancer research : CR

    pub_type： 杂志文章

    doi：

    authors： Babovic N,Jelic S,Jovanovic V

    更新日期：2000-06-01 00:00:00